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Calprotectin (Human)人钙保护素 酶联免疫试剂盒

 

人钙保护素是一个诊断结肠癌的可靠的生物标示物

Calprotectin (人） 酶联免疫试剂盒
产品号 SK00259-01
包装 2 x 96 T
标准曲线范围: 1.6-100 ng/ml
检测灵敏度 1.6 pg/ml
检测时间 4小时
样本体积 100 ul
样本稀释 60 (EDTA plasma)
正常值 500- 3000 ng/ml
批内误差 6.2%
批间误差 9.3%
交叉反应 人Calprotectin 100%,

Calprotectin elisa

 

 

 

 

 

 


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电话号码 010-81786624； 010-81786244

试剂盒名称
用途
目录号
规格
价格(元)
人钙保护素 酶联免疫试剂盒
进口原装
SK00259-01
2 x 96T
11960
人钙保护素 多克隆抗体
进口
AB00259-02
100 ug
5400
人钙保护素 单克隆抗体
进口原装
AB00259-03
100 UG
5400

 

Faecal calprotectin and faecal occult blood tests in the diagnosis of colorectal carcinoma and adenoma
BACKGROUND AND AIMS---Testing for faecal occult blood has become an accepted technique of non-invasive screening for colorectal neoplasia but lack of sensitivity remains a problem. The aim of this study was to compare the sensitivity and specificity of faecal calprotectin and faecal occult blood in patients with colorectal cancer and colonic polyps.
METHODS---Faecal calprotectin and occult blood were assessed in 62?patients with colorectal carcinoma and 233?patients referred for colonoscopy. The range of normality for faecal calprotectin (0.5-10.5 mg/l) was determined from 96?healthy subjects.
RESULTS---Median faecal calprotectin concentration in the 62?patients with colorectal carcinoma (101?mg/l, 95% confidence interval (CI) 57-133) differed significantly from normal (2.3?mg/l, 95% CI 1.6-5.0) with 90% of patients having elevated levels (normal <10 mg/l) whereas only 36/62 (58%) had positive faecal occult bloods. There was no significant difference in faecal calprotectin levels when considering location or Dukes' staging of tumour. Percentage positivity of faecal occult bloods was significantly higher for Dukes' stage C and D cancers compared with Dukes' A and B.?In the colonoscopy group, 29?patients with adenomatous polyps were detected in whom the median faecal calprotectin was 12?mg/l (95% CI 2.9-32). Sensitivity for detection of adenomatous polyps was 55% using the calprotectin method and 10% using faecal occult blood testing. The overall sensitivity and specificity of calprotectin for colorectal cancer and adenomatous polyps as a combined group was 79% and 72%, respectively, compared with a sensitivity and specificity of faecal occult blood of 43% and 92%.
CONCLUSIONS---Faecal calprotectin is a simple and sensitive non-invasive marker of colorectal cancer and adenomatous polyps. It is more sensitive than faecal occult blood tests for detection of colorectal neoplasia at the cost of a somewhat lower specificity.
Gut 2001;49:402-408 (?September?)

 

 

 

 

 

 
 
脂肪因子的创新研究