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HSL 激素敏感脂酶(Hormone Sensitive Lipase,HSL是一个代谢综合征标示物

脂肪组织是脊椎类生物最重要的能量储存库。这个脂肪库的维持是一个动态平衡调节,即脂肪的合成(成脂)和脂肪的分解(异脂)之间的动态平衡。任何因素引起这一动态平衡的紊乱或是失平衡,导致代谢紊乱、代谢综合征、肥胖和二型糖尿病的发生和发展。游离脂肪酸从脂肪组织的释放依赖于脂肪酶的水解活性。过去一般认为,激素敏感的脂肪酶是主管细胞脂肪分解的关键酶。

 

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Product Name Catalog No.
Size
Price
HSL (Mouse) Antibody IgY for WB A00502-02
100 ug
1000
HSL (Human, Mouse) Rabbit Antibody A00502-06
100 ug
2855
HSL (Human, Mouse) Rabbit Antibody A00502-05
100 ug
4180
HSL (Human) MAB for IP, WB A00502-01
200 ug
3376
HSL (Mouse) Antibody IgY for WB A00502-02
100 ug
1000
HSL (Mouse) Antibody IgY for WB A00502-03
100 ul
2000

 

Confocal immunofluorescent analysis of 3T3-L1 adipocytes using HSL Antibody (red, A00502-06). Lipid droplets have been labeled with BODIPY 493/503 (green). Blue pseudocolor = DRAQ5? (fluorescent DNA dye).
Western blot analysis of extracts from NIH/3T3 and 3T3-L1 cells using HSL Antibody (A00502-06).
HSL was detected in Mouse and rat adipocytes lysate by Anti-HSL (Mouse) IgY [ A00502-02] at 1:2000 -5000
Western blot analysis of HSL expression in BT-20 (A) and SK-BR-3 (B) whole cell lysates by HSL MAB [A00502-01]
by A00502-05

Immunocytochemistry analysis of HSL expression in the small intestine. A, HSL immunoreactivity in the jejunal section. B, control micrograph performed in the jejunal section without anti- HSL antibody. C, HSL immunoreactivity in the ileal section. D, control micrograph performed in the ileal section without anti-HSL antibody.

 

 

 



 
脂肪因子的创新研究