心脏型脂肪酸结合蛋白 HFABP是研究心血管疾病心肌梗死一个可靠的生物标示物

Fatty acid-binding proteins (FABP) are tissue specific intracellular molecules of about 15 kD. They are a class of cytoplasmic proteins that bind long chain fatty acid and play an important role in the intracellular utilization of fatty acids. Different types of FABP have
been detected and these include Heart FABP, Liver FABP and Intestinal FABP, etc. Human cardiac muscle has high content of FABP (10-20 mol % of cytoplasmic proteins). Heart FABP (H-FABP) is a sensitive biomarker of myocardial necrosis that can be used to
confirm or exclude a diagnosis of acute myocardial infarction (AMI) and for monitoring of a recurrent infarction3. In AMI, H-FABP is rapidly released from damaged cardiomyocytes into the circulation due to its small size. H-FABP levels are significantly elevated above
their threshold level within 3 hours after AMI and subsequently return to normal values in 12 to 24 hours7. More recently, H-FABP has been identified as a potential serum biomarker for stroke that is superior to either neuron specific enolase or S100B8.
The normal levels of H-FABP range from 1.6 ng/ml to an upper level of 19 ng/ml in various studies of cardiovascular disease1-7. H-FAB increases slightly with age.

人心脏型脂肪酸结合蛋白酶联免疫试剂盒 [SK00213-06]可以检测血清的样本。健康人的含量在 1.6 ~ 18 ng/m， 超过19ng/ml考虑有急性心肌梗死的发生l; 灵敏度（Sensitivity ）： 0.5ng/ml； 标准曲线范围是0.31-20ng/ml。SK00213-01试剂盒需要样本体积100微升；

Protocol

脑型脂肪酸结合蛋白说明书

脑型脂肪酸结合蛋白说明书

抗体说明书

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