Gas6, a Biomarker fo Cardiovascular Diseses

ELISA name Human Gas6 ELISA Kit Code SK00098-01 Size 96 T Test Range 125-8000 pg/mL Sample Vol. 100 ul Sample Type Serum, EDTA Plasma, Saliva Normal Value 18.0 +- 2.5 ng/mL Dilution Factor 5-10 检测操作时间 4 hours intra CV <6.5% Inter CV <10% ELISA name Mose Gas6 ELISA Kit Code SK00098-03 Size 96 T Test Range 39-2500 pg/mL Sample Vol. 100 ul ( 50 x dilution required) Sample Type Serum, EDTA Plasma, Saliva Normal Value 20 ng/mlL Preeclampsia   检测操作时间 4 hours intra CV <4.5% Inter CV <7% The growth arrest-specific genes are related by their induction following cellular stress. Gas1 is a GPI-linked membrane glycoprotein that blocks entry to S phase cell cycle. Gas1 inhibits cell proliferation, protects endothelial cells from apoptosis, and promotes excitotoxic neuronal death. Gas6 is a vitamin K-dependent protein with a gamma-carboxylated amino terminus (Gla domain), four EGF-like repeats, and C-terminal globulin-like domains. Gas6 is a ligand for the Axl, Dtk, and Mer tyrosine kinase receptors. Gas6 is mitogenic and anti-apoptotic for some cell types and also promotes cell adhesion.

产品名称	目录号	规格	价格
Human Gas6 ELISA Kit	SK00098-01	96 T	询价
Mouse Gas6 ELISA Kit	SK00098-03	96 T	询价

 

订货电子信箱：Info@Adipobiotech.com

订货电话号码: 010-81786624; 010-81786244

Overall architecture of the Gas6-LG/Axl-IG complex. Shown are three orthogonal views. (A) Top view, towards the cell membrane harbouring the receptor. (B) Side view, with the cell membrane at the bottom. (C) Front view, in the direction indicated by the arrow in (B). Surface representations are shown in (A) and (B), while a cartoon representation is shown in (C). Gas6-LG is in cyan (N-terminal segment and LG1) and green (LG2), Axl-IG is in yellow (IG1) and brown (IG2). In (C), the Gas6-LG molecule at the back has been removed for clarity, a calcium ion in the LG1–LG2 interface is shown as a pink sphere, and the Gas6/Axl contact sites are labelled. EMBO J. 2006 January 11; 25(1): 80–87.