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Antibody for Metabolic Syndrome Research
Insulin Ab   insulin Rab   C Peptide Antibody   Glucagon Antibody
Insulin Rabbit MAb
Price: ¥2856
  Insulin Rabbit PAb
Price: ¥2856
  C Peptide RPAb
Price: ¥2856
  Glucagon RPAb
Price: ¥2856
 
Insulin Mab            
Insulin Mice MAb
Price: ¥700
 
 
 
 

 

No.
Name
Price : RMB
CS3014 Insulin (C27C9) Rabbit mAb
2856
A00060-02 Insulin Mice Mab
700
CS4590 Insulin Rabbit Ab
2856
CS4593 C Peptide Rabbit Ab
2856
CS2760 Glucagon Rabbit Ab
2856

Glucagon Rabbit Antibody CS2760

Catalog #
Size
Price (RMB)
CS2760
100 ul (100 sections)
2856
Applications
Reactivity
MW (kDa)
Source
IHC-P IF-F
H M R
4
Rabbit

Applications Key:  IHC-P=Immunohistochemistry (Paraffin)  IF-F=Immunofluorescence (Frozen)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species enclosed in parentheses are predicted to react based on 100% sequence homology. Species cross-reactivity is determined by Western blot.

Specificity / Sensitivity

Glucagon Antibody detects endogenous levels of total glucagon protein.

Source / Purification

Polyclonal antibodies are produced by immunizing rabbits with a synthetic peptide (KLH-coupled) derived from the sequence of human glucagon. Antibodies are purified by protein A and peptide affinity chromatography.

IHC-P (paraffin)

IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded human pancreas, showing staining of α cells, using Glucagon Antibody.

IHC-P (paraffin)

IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded mouse pancreas, showing staining of α cells, using Glucagon Antibody.

IF-F

IF-F

Confocal immunofluorescent analysis of normal mouse pancreas using Glucagon Antibody (green). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye).


Background

Glucose homeostasis is regulated by a variety of hormones including glucagon. Glucagon is synthesized as the precursor molecule proglucagon and is proteolytically processed to yield the mature peptide in α cells of the pancreatic islets. Glucagon causes the release of glucose from glycogen and stimulates gluconeogenesis in the liver (1,2).

  1. Hers, H.G. and Hue, L. (1983) Annu. Rev. Biochem. 52, 617-653.
  2. Granner, D. and Pilkis, S. (1990) J. Biol. Chem. 265, 10173-10176.