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Glucagon Rabbit Antibody CS2760
Applications Key: IHC-P=Immunohistochemistry (Paraffin) IF-F=Immunofluorescence (Frozen) Specificity / SensitivityGlucagon Antibody detects endogenous levels of total glucagon protein. Source / PurificationPolyclonal antibodies are produced by immunizing rabbits with a synthetic peptide (KLH-coupled) derived from the sequence of human glucagon. Antibodies are purified by protein A and peptide affinity chromatography. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human pancreas, showing staining of α cells, using Glucagon Antibody. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded mouse pancreas, showing staining of α cells, using Glucagon Antibody. IF-F
Confocal immunofluorescent analysis of normal mouse pancreas using Glucagon Antibody (green). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye). BackgroundGlucose homeostasis is regulated by a variety of hormones including glucagon. Glucagon is synthesized as the precursor molecule proglucagon and is proteolytically processed to yield the mature peptide in α cells of the pancreatic islets. Glucagon causes the release of glucose from glycogen and stimulates gluconeogenesis in the liver (1,2). |
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